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Case Studies

A woman with lipedema grasps her thigh.

There's More Than One Way to Treat Lipedema

Surgery may not always be the best option, case report finds

A photo of a boy holding a tablet displaying an xray of his jaw in front of his face.

BRAF Inhibition in Pediatric Ameloblastoma of the Jaw

Targeted therapy in 3 boys allowed for conservative surgery to restore jaw to predisease state

A close up of an Asian woman receiving a neck ultrasound.

What's the Cause of Neck Swelling, Fever in Young Woman?

Diagnosis of this rare disease is often a challenge

A photo of a spilled jar of gummy bears.

What Caused Acute Encephalopathy in This Young Child?

Clinicians found 2-year-old girl barely responsive to stimuli

An Asian woman lies in a CT scanner.

Rare Case of Multiple Myeloma in Teenage Girl

Successful use of affordable induction therapy with autologous stem cell transplantation

X-ray of an elderly woman showing pleural effusion of the left lung.

What Is the Cause of Persistent Pleuritis in Lung Cancer Patient?

Diagnosis of exclusion pointed to one agent, 6 months after treatment was completed

A computer rendering of bladder cancer.

Rare Aggressive Bladder Cancer Treated Successfully in Elderly Man

Neoadjuvant chemotherapy followed by cystectomy achieves complete response

A close up of Merkel cell carcinoma on a person鈥檚 arm.

Case: VEGFR Inhibition in Merkel Cell Carcinoma Patient

Disease stabilized after post-chemotherapy progression of the aggressive neuroendocrine cancer

A male physician wearing a protective mask as seen through the chest x-ray he is holding.

Invasive Pneumococcal Disease in Older Man, but There's a Worse Problem

Warning to be alert for this underlying cancer in older patients with bacterial/viral infections

A computer rendering of renal cancer.

Diagnosis of Mass Confined to the Kidney: Is It RCC or TCC?

Ureteroscopy and histopathology should be considered as routine preoperative assessments

A male technician performs an ultrasound on an out of focus pregnant woman

Large Uterine Fibroid in Pregnant Woman

Cesarean myomectomy of large fibroids is safe in the right setting

A computer rendering of an aortic aneurysm

Rare Case of a Patient Who Survived This Cardiovascular Condition

Here's how surgeons discovered and successfully excised the problem

A photo of a woman鈥檚 swollen feet.

Warning: Patient's Itchy Swollen Skin Patches Were Not Infectious Cellulitis

Five years of inappropriate antibiotic treatment finally ended after proper diagnosis

Photo of 72-year-old woman being evaluated for mild pain and joint stiffness in her hand.

What's Causing Cancer Patient's Joint Pain While on Checkpoint Inhibitor?

Here is how clinicians diagnosed this rare inflammatory side effect

Empty nitrous oxide cartridges and balloons lay in a field.

Neuropathy After Recreational Use of Laughing Gas

Clinicians should be aware of adverse effects of this increasingly popular drug

A close up of blue rubber gloved fingers holding a vial labeled: Tdap Vaccine

Did Tdap Shot Delay Immunogenicity of COVID Vaccine?

Serology tests were requested by healthcare worker who fell a day after her COVID vaccine

A close up of a woman wearing a protective mask receiving the COVID-19 vaccine.

Woman Develops Tiny Blood Spots on Her Body After COVID Shot

Case highlights need for quick diagnosis and management of rare disorder

A female nurse measures the height of a young boy.

Teen Seeks Care for Delayed Growth Compared With His Twin

Case shows confluence of hormone therapy cost and limited resources in developing areas

Photo of an athlete resting and refreshing with cold water.

Triathlete Seeks Help After Repeated Spells of Heart Palpitations

Sports career/training can trigger Afib

A close up of a senior woman鈥檚 blue eye.

Unexplained Catatonia: What's Behind Woman's Sudden Symptoms?

Recent history of insomnia could be a clue

A male physician palpates the swollen thyroid of his young adult female patient.

What Caused This Otherwise Symptom-Free Woman's Neck Mass?

Case shows possible dangers even in hyperfunctioning "hot versus hypofunctioning "cold nodule

CT imaging of primary ameloblastoma with measurement and three-dimensional reconstruction.

Woman Loses 6-Year Battle With Mouth Tumor

Rare ameloblastoma rapidly recurs and metastasizes despite numerous radical excisions

A close up of a young woman smoking marijuana.

What's Causing the Severe Stomach Pain and Vomiting in Teen Pot Smoker?

She is found to have COVID-19, but another serious problem is almost missed

A close up of a deer tick on a person's skin

Single Tick Bite Packs Triple Punch

Patient presents with Lyme disease plus anaplasmosis and babesiosis co-infections

An MRI image of sclerosing mesenteritis

Diabetic Man With Sclerosing Mesenteritis Experiences Glycemic Control With Steroids

Case authors report an unexpected paradoxical effect

A close up of a female doctor performing an ultrasound on her patients arm.

Teen Develops Persistent, Spreading Arm Swelling After a Fall

Is it "just" a hematoma or something more sinister?

A blister pack of Clozapine tablets over a computer rendering of the human heart

Avoiding Clozapine-Related Risks in Refractory Schizophrenia

Key is to recognize and safely diagnose one possible deadly complication

A micrograph of clear cell renal cell carcinoma

How Did a Patient Survive a Decade With Metastatic RCC?

Surgery had beneficial role

A mature woman with her hands on her chest experiencing pain

What's Behind the Mysterious Chest Pain in Bladder Cancer Patient?

Cardiomyopathy risks interrupting cancer treatment, worsening prognosis

A teen female is nearly obscured by the enormous vape cloud she exhaled

Did Vaping THC 'Wax' for 5 Days Cause This Teen Girl's Seizure?

Evidence for the effect of THC on seizure threshold is conflicting, clinicians say

Urography showing a large polypoid mass in the bladder

What to Do With a Rare, Aggressive Bladder Cancer

Case authors lament scant information on treatments or outcomes

A man with his hand to his ear struggles to hear

What's Behind This Sudden Hearing Loss in Both Ears?

Key to recovery was immediate work-up for one specific condition

A computer rendering of the Varicella-zoster virus

Why the Sudden Onset of Severe Abdominal Pain, Then a Rash?

Watch out for atypical presentations, clinicians warn

A mature man holds his painful right buttock

Where Did This Very Painful Gluteal Mass Come From?

High clinical suspicion, low threshold for biopsy key to diagnosis

A computer rendering of a liver with cirrhosis

How Does Underlying Cirrhosis Affect COVID-19?

Beware of secondary bacterial infections, case report suggests

A computer rendering of a transparent body with a liver with cirrhosis highlighted

Word of Caution on Angiogenesis Inhibitor for Liver Cancer

Case report highlights risk of serious adverse effects

A photo composite of a womans hand with her third finger tip severed

The Case of the Lost Fingertip

Was conservative management the right choice?

A woman receives an ultrasound of her neck

Recurring Condition in This Woman Remained Undiagnosed for 13+ Years

"Great masquerader" can resemble many other dangerous diseases

A woman wearing an oxygen mask lies in a hospital bed in front of a monitor displaying her vitals

A Novel Tx for Severe COVID-19 Pneumonia

All three patients described were able to avoid ICU admission

A woman about to undergo a gastroscopy

A Life-Threatening Problem Hidden Within a Hiatal Hernia

Condition resolved after clinicians used a novel oral combination

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