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Parkinson's Disease

News, opinions and meeting coverage in neurology.

Lifespan in Parkinson's Tied to Early Symptoms

Normal cognition early in PD predicted normal life expectancy

Parkinson's Gene Therapy Shows Signs of Motor Improvement

Early open-label trial in advancing Parkinson's disease showed treatment was safe, well-tolerated

Blood Biomarker Distinguishes Parkinson's from MSA

Alpha-synuclein levels in brain-derived exosomes highlight differences

Robots and Surgery; Alcohol and Death: It's PodMed Double T!

This week's topics include Parkinson's disease and metabolic syndrome, lorcaserin and heart problems, the global burden of alcohol related disease, and robotic surgery costs.

Does Work Stress Increase Parkinson's Risk?

High-stress jobs tied to PD in men, but high-control jobs had stronger link in women

Elephants and Alzheimer's; Omega-3 and Epilepsy; Eye Disease and Dementia

News and commentary from the world of neurology and neuroscience

Lewy Body Disease Tied to Contact Sports

More than 8 years of play linked to Lewy bodies, parkinsonism

DBS Shows Promise in Early-Stage Parkinson's

Findings in pilot study suggest rest tremor progression may be slowed

Bacteriophages: Hidden Players in Parkinson's Disease?

Viruses affect microbiome composition, perhaps fostering rogue neural proteins

Immunosuppressants Linked to Lower PD Risk

Corticosteroids, IMDH inhibitors show strongest associations

Novel Endocannabinoid Modulator Improves Tics in Tourette's

In small study, total number, intensity decreased with minimal side effects, although no change for vocal tics

AAN 2018: Rare Disease Breakthroughs and Novel Approaches

Noteworthy presentations at American Academy of Neurology meeting

Wrist-Worn Device Reduces Hand Tremor

Neuroperipheral therapy interrupts signal in essential tremor patients

Coffee and Cannabis; Stephen Hawking鈥檚 ALS; New Stroke Risk Loci

News and commentary from the world of neurology and neuroscience

NeuroBreak: Hits, Not Concussions, Cause CTE; Smoking and PD; APOE4 News

News and commentary from the world of neurology and neuroscience

CDC: White Collar Jobs Tied to Neurodegenerative Disease Deaths

ALS, Parkinson's mortality more common in highly educated workers

Caffeine No Help for Motor Function in Parkinson's

Randomized controlled trial clashes with epidemiologic data

Anti-Tau Drugs for PSP Move into Phase II

But phase I study of one agent pulled from presentation

Inhaled Levodopa Cuts Motor Symptoms in Parkinson's 'Off' Episodes

Drugmaker Acorda to seek FDA approval shortly

Sleep Aid Tied to Parkinson's Risk

But meta-analysis includes only two Taiwanese claims studies

FDA Eyeing Patient-Reported Outcomes in Huntington's, Parkinson's

Some non-motor symptoms may be ideal 'PRO' candidates

Wise Buy? Focused Ultrasound Therapies

Exciting technology, but now sold to patients on slim supporting evidence

Novel Parkinson Therapies Highlighted at AAN Meeting

Early results with gene therapy, new carbidopa-levodopa formulation featured

Fraud Rounds: Four Retractions Tallied for PD Researcher Spared Jail

Faking co-author signatures, consent forms, and duplication adds up

ADHD Drug Fails to Boost Cognition in Parkinson's

But patients reported improvements in impulsivity, inattention

Quick Enrollment for STEADY-PD III Trial

Researchers enrolled 336 early Parkinson's patients within a year

Parkinson's GI Issues More Complex than Constipation

Study reveals IBS risk

Anxiety Overlooked in Parkinson's?

Longitudinal study finds 16% have baseline anxiety, 37% develop it over time

Physical Therapy Underused in Parkinson's

Only 11% of patients had used it in Medicare study

PD Patients Report Better Sleep With Rotigotine Tx

Patch form of dopamine agonist also lowered nighttime activity

Inhaled Levodopa May Bridge Parkinson's 'Off' Periods

Inhaler eased breakthrough motor symptoms between standard levodopa doses in an early study

Subcutaneous Apomorphine Gets Parkinson's Patient Moving Quickly

Most patients respond to injected drug within 20 minutes

Stroke Survivors May Face Greater Cancer Risk

Ischemic stroke increased likelihood of cancer within 2 years of the event.

FDA OKs Northera for Hypotension

The FDA has approved droxidopa (Northera) for the treatment of neurogenic orthostatic hypotension, a rare disease that results in a drop in blood pressure when patients try to stand up.

Droxidopa for OH Slammed by FDA Reviewers

SILVER SPRING, Md. -- Droxidopa (Northera) is getting a second look by an FDA advisory committee for the treatment of orthostatic hypotension stemming from neurological disorders like Parkinson's disease, but an agency review doesn't look promising for approval.

Aricept Helps Cognition in Parkinson's

SYDNEY -- Parkinson's disease patients who have impaired cognition appeared to benefit from the Alzheimer's disease medicine donepezil (Aricept) with no detriment to their motor skills, researchers reported here.

Eye Tremors May Be Early Sign of Parkinson's

Eye tremors are pervasive in Parkinson's disease and could be an early warning sign of the neurodegenerative movement disorder, according to a case-control study.

Parkinson's Called Hidden Killer

Life expectancy for patients with Parkinson's disease is poorer than some previous studies have suggested, with barely one-third of patients surviving six years with the condition, researchers said.

Jumpy Legs in Parkinson's Likely Not RLS

Patients with early Parkinson's disease were more likely to have a movement disorder called leg motor restlessness than true restless legs syndrome, a study found.

Parkinson's Drug Doesn't Slow Disease Progress, FDA Staff Says

WASHINGTON -- Azilect (rasagiline), which is already approved to treat symptoms of Parkinson's disease, does not appear effective at slowing progression of the neurodegenerative disease, according to an FDA review.

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