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Previous research shows that adenoma detection rates (ADRs) and adenoma characteristics are both associated with colorectal cancer (CRC) incidence and mortality. However, the impact of the two factors combined has not been studied.

In this study recently published online in , Waldmann et al. sought to assess the combined effect of ADRs and adenoma characteristics on the risk of CRC incidence and mortality. They found that adding ADR to the risk stratification model improved risk assessment in all risk groups. Additionally, stratification improved most for patients with high-risk adenomas.

Although the study did not adjust for comorbidities and lifestyle risk factors for CRC, it does add important evidence for mandatory assessment and monitoring of performance quality in screening colonoscopy. Based on the clinical significance of this work, combining ADR and adenoma characteristics could reduce post-screening incidence of CRC and mortality rates.

Melinda Engevik, PhD, is an assistant professor at Medical University of South Carolina in Charleston.

You can read an interview with two of the study's authors here, and the abstract of the study here.