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General Hepatology

News, opinions and meeting coverage in gastroenterology.

Photo of a press conference in The Woodland, Texas.

Houston Transplant Scandal: Families of Patients Who Died Begin Legal Action

Surgeon has been accused of manipulating waitlist, making his patients ineligible for new livers

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Cancer Warnings on Booze; Rats, Roaches in Hospitals; Barefoot Pharma Workers

Health news and commentary from around the Web gathered by 名媛直播 staff

A colorized electron microscope image of a hepatitis C virion.

Start of a New Trend? Hepatitis C Cases Drop in the U.S.

After a decade of increases, health officials aren't sure if change is just a statistical blip

A photo of a glass of white wine next to the bottle on a kitchen counter with food cooking on the stove in the background.

More Women Are Drinking Themselves Sick. The Biden Administration Is Concerned.

But change isn't something everyone will raise a glass to

Aspirin for Fatty Liver; Meds for Self-Managed Abortion

Also in TTHealthWatch: diagnosing Parkinson's with a skin biopsy

Photo of an elderly woman signing discharge papers at a hospital exit area.

Starting Treatment at Discharge for Alcohol-Related Hospital Stays Shows Benefits

However, only 2% of hospitalized patients received a script

A photo of a physician using a FibroScan device on their male patient.

VCTE-Based Agile Scores Accurate in Predicting Liver-Related Events in MASLD

Serial Agile scores were also accurate over time

A photo of a spilled bottle of low dose aspirin tablets

Aspirin Cuts Liver Fat in Preliminary MASLD Trial

At 6 months, 42.5% of patients on low-dose aspirin had at least a 30% reduction in hepatic fat

FDA APPROVED resmetirom (Rezdiffra) over a computer rendering of a transparent body with the liver highlighted.

FDA Approves First-Ever Drug for Serious Liver Condition

Resmetirom indicated for NASH patients with liver scarring

Deaths Due to Alcohol Use; Steps for the Sedentary

Also in TTHealthWatch: microplastics in arteries, and worldwide obesity and diabetes risk

CROI over a photo of Colorado Convention Center in Denver, CO

Semaglutide Cuts Liver Disease Severity in People With HIV

Weekly injections reduced liver fat by 31% at 6 months

A computer rendering of a capsule in front of a fatty liver.

SGLT2 Inhibitors Tied to Better NAFLD Outcomes vs Other Antidiabetic Agents

Class of drug associated with highest odds of NAFLD regression for patients with type 2 diabetes

New Treatment for NASH; Human Milk for Preterm Infants

Also in TTHealthWatch: managing gout with uric acid levels

A photo of a surgeon opening a plastic bag containing a donor liver.

Stigmatizing Language Common on Liver Transplant Websites

Researchers searched for terms including "alcoholic," "alcoholism," and "alcohol abuse"

A computer rendering of a healthy liver, a fatty liver, and a cirrhotic liver

Resmetirom Poised to Become First NASH Treatment

Phase III study demonstrated drug is effective in resolving NASH and improving liver fibrosis

A computer rendering of a diseased liver.

Undiagnosed Liver Disease May Be Common in Patients With Dementia

Hepatic encephalopathy could be contributing to cognitive symptoms, study suggested

Composited optical coherence tomography images

Can the Eye Reveal Cardiac and Lung Disease -- Plus Much More?

Researchers link thinner retinal layers to higher risk of multiple diseases

GiCS over a photo of Moscone Convention Center West in San Francisco, CA

HAIP Chemo Offers OS Advantage in Advanced Intrahepatic Cholangiocarcinoma

One in three trial patients still alive at 3 years after hepatic arterial infusion pump treatment

A computer rendering of a transparent pic with opaque organs

First-Ever Experiment Shows How Pigs Could One Day Help Liver Failure Patients

Penn surgeons externally attached gene-edited pig liver to brain-dead human

A computer rendering of a fatty liver.

Subclasses of Steatotic Liver Disease Can Help Determine Prognosis

Risk of liver decompensation increased progressively when alcohol intake came into play

A photo of a box of Lenvima capsules over a computer rendering of hepatocellular carcinoma

Lenvatinib-Pembrolizumab Combo Misses Goal in First-Line HCC Trial

Numerical advantages in OS, PFS fall short of statistical significance

A photo of surgeons performing a liver transplant.

Mahvash Disease Case Resolved With Liver Transplantation

Rare disease should be part of the differential in the presence of massive pancreaticomegaly

AASLD over a photo of Hynes Convention Center in Boston, Massachusetts

PPAR Agonist Led to 'Clinically Meaningful' Improvement in PBC-Related Pruritus

Seladelpar also improved markers of disease activity versus placebo

AASLD over a photo of Hynes Convention Center in Boston, Massachusetts

Novel MASH Drug Reduces Liver Fat in Mid-Stage Trial

At highest dose, thyroid hormone receptor-beta agonist decreased liver fat content by 45%

AASLD over a photo of Hynes Convention Center in Boston, Massachusetts

Emergency Liver Transplant Effective for Severe Acute-on-Chronic Liver Failure

1-year survival reached 78% for patients who received an emergency transplant

AASLD over a photo of Hynes Convention Center in Boston, Massachusetts

Novel Drug Makes Its Case for Pretreated Primary Biliary Cholangitis

In randomized trial, oral elafibranor induced biochemical response at 1 year in 51% of patients

AASLD over a photo of Hynes Convention Center in Boston, Massachusetts

AKI Response Tied to Improved Survival for Patients Waiting on Liver Transplant

Results highlight the importance of prompt recognition and treatment of acute kidney injury

AASLD over a photo of Hynes Convention Center in Boston, Massachusetts

MASLD Predicted to Increase by 23% by Middle of the Century

AASLD president: "No way we are going to be able to transplant our way out of this"

Diet and Liver Health; Gut Microbiome and Cardiometabolic Disease

Also in TTHealthWatch: COVID hospitalization data

A computer rendering of a transparent body with the liver highlighted.

Cancer Risk in NAFLD Higher With Early Disease Onset

52% greater risk of malignancy for patients diagnosed with fatty liver disease before age 45

A close up of a woman鈥檚 eye yellowed by jaundice.

Gene Therapy Promising for Rare Jaundice Syndrome

Early-phase data suggest a dose that can keep bilirubin in check without hours of phototherapy

FDA APPROVED melphalan/Hepatic Delivery System (Hepzato Kit) over a CT scan of liver metastasis

FDA OKs First Liver-Directed Treatment for Metastatic Uveal Melanoma

Hepzato Kit melphalan delivery system produced objective responses in 36% of patients

A photo of a spoonful of aspartame-based sweetener in front of the container it came from.

Aspartame Is a 'Possible' Carcinogen, WHO Declares

But the organization's recommended limits on aspartame consumption remain unchanged

A close up photo of a man testing his blood sugar with a glucose meter.

NAFLD and T2DM Bodes Higher Risk of Liver Decompensation, Cancer

Several-fold higher risks compared with NAFLD patients without diabetes

A computer rendering of a hepatitis C virus in the bloodstream.

'Jarringly' Low Hep C Cure Rates a Decade After New Treatments, CDC Says

Lack of rapid testing and payer restrictions are creating barriers, experts say

ADA over a photo of the San Diego Convention Center in San Diego, CA.

Novel Triple Agonist Nabs Biggest Weight Loss Yet in Obesity Trial

Plus, two other studies on retatrutide show benefit in type 2 diabetes, fatty liver disease

EASL over a photo of Messe Wien Exhibition Congress Center, Wien, Austria

Can AI Help Determine if Liver Cancer Will Respond to Standard Treatment?

Early model suggests a way to predict progression-free survival

EASL over a photo of Messe Wien Exhibition Congress Center, Wien, Austria

Fecal Matter Transplant Shows Promise in Cirrhosis

Pilot trial demonstrates that FMT can boost gut health, prevent serious infections

EASL over a photo of Messe Wien Exhibition Congress Center, Wien, Austria

'Game Changer' in NASH: Resmetirom Hits Endpoints in Pivotal Study

Investigational drug more likely to resolve severe form of fatty liver disease, improve fibrosis

FDA ADCOMM obeticholic acid (Ocaliva) over a computer rendering of a liver with fibrosis.

Ocaliva for NASH Gets Thumbs Down From FDA Advisors

Difficulty of risk mitigation for potential drug-induced liver injury weighed heavily on members

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