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Alzheimer's Disease

News, opinions and meeting coverage in geriatrics.

A photo of bottles of galantamine supplement capsules.

Alzheimer's Supplements Fail Compared With Generic Drugs

Prescription galantamine drugs were labeled accurately, but dietary supplements were not

A computer rendering of nerve cells affected by Alzheimer鈥檚 disease.

Alzheimer's Biomarkers Show Specific Changes 20 Years Before Diagnosis

CSF and imaging markers changed in a temporal sequence

A computer rendered cutaway of a blood flowing through a vessel

Dementia Predicted 10 Years Before Diagnosis

Blood proteins identified those at risk for all-cause, Alzheimer's, or vascular dementia

A photo of PDE5 inhibitor erectile dysfunction drugs

Erectile Dysfunction Drugs Tied to Less Alzheimer's Risk

Large U.K. study tracked health records of 270,000 men

A computer rendering beta amyloid accumulating between neurons

Even With Alzheimer's Pathology, Healthy Lifestyles May Preserve Cognition

More data support the idea of "cognitive reserve"

A photo of the packaging and vial of Aduhelm.

Controversial Alzheimer's Drug Abandoned

Biogen will stop developing and selling aducanumab

A computer rendered progression of neuron damage in Alzheimer鈥檚 disease

Alzheimer's May Be Transmissible in Rare Circumstances

Cases tied to long-discontinued childhood medical procedure

A photo of a tube of blood labeled Alzheimer鈥檚 disease held in blue rubber gloved hands in front of MRI images of a brain.

Alzheimer's Blood Test Shows High Diagnostic Accuracy

Commercial ptau-217 assay reduced confirmatory testing by about 80%

A photo of two faceless mannequins.

Face Blindness Is Not Always Permanent

Largest study to date looks at inability to recognize familiar faces

Open Blood-Brain Barrier for Alzheimer's Treatment?; Managing TMD

Also in TTHealthWatch: IV drug for early atrial fibrillation

A composite image of an Amsler grid laying over a photo of a persons eye

Dementia Drugs Seen Lowering Risk for Macular Degeneration

But not by very much or very quickly, VA analysis finds

A computer rendering of a patient who is receiving focused ultrasound

Opening Blood-Brain Barrier to Deliver Alzheimer's Drug Shows Promise

Focused ultrasound helped aducanumab reduce amyloid-beta levels

A computer rendering of a nerve cell affected by Alzheimer鈥檚 disease

Novel Alzheimer's Trials Evaluate Senolytics, Semaglutide, CRISPR, and More

Looking ahead to 2024 and beyond: "There is so much more to be done"

A photo of a test tube of blood labeled: Alzheimer鈥檚 disease, laying on a stainless tray.

Alzheimer's Blood Test Predicts Who Might Benefit Most From Anti-Amyloid Drugs

Novel two-cutoff approach may reduce need for confirmatory PET scans

A computer rendering of an artery narrowed by plaque.

Coronary Heart Disease by Age 45 Linked With Subsequent Dementia

All-cause dementia, Alzheimer's disease, and vascular dementia risks elevated

A photo of a senior man sitting over a puzzle and talking on a smartphone.

Cognitive Scores Improve With Personal Coaching

Trial shows better outcomes for people at high dementia risk

A computer rendering of amyloid plaques clumped between nerve cells.

Alzheimer's Drug Trials Should Report Effect Sizes, Researchers Say

How effective are anti-amyloid treatments?

A photo of a blue rubber gloved hand holding a test tube labeled: TOTAL PROTEIN TEST

Proteins Predict Signs of Alzheimer's Disease

Subclinical health indicators tied to markers of Alzheimer's and neurodegeneration

A computer rendering of the brain with the hippocampus highlighted.

Hippocampal Atrophy Might Not Signal Alzheimer's Disease

Measuring tau and hippocampus in addition to amyloid may improve Alzheimer's diagnosis

A computer rendering of amyloid beta peptide.

Gantenerumab Failed to Slow Cognitive Decline in Early Alzheimer's

Amyloid plaque levels went down, but not enough for clinical benefit

A photo of foods associated with the MIND diet.

MIND Diet in Midlife Tied to Higher Subcortical Brain Region Volumes

Relationships appear to hold regardless of Alzheimer's genes

A computer rendering of amyloid plaques collecting between neurons

Subcutaneous Alzheimer's Drug May Be on the Horizon

Investigational version of lecanemab shows promise, but questions about safety persist

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Dianne Feinstein Dies; Prison for Alzheimer's Fraudsters; Kaiser Strike Looming

Health news and commentary from around the Web gathered by 名媛直播 staff

A photo of a senior man receiving chemotherapy in an infusion clinic.

Experts Warn on Mixing New Alzheimer's Drug and Antidepressants

Patients starting SSRIs and lecanemab may warrant close monitoring

A computer rendering of amyloid plaques on a nerve cell.

Few Early Alzheimer's Patients Qualify for Lecanemab

Inclusion and exclusion criteria whittle down pool of eligible treatment candidates

A photo of the reception area of a Quest Diagnostics clinic.

Quest's Alzheimer's Blood Test Has Experts Concerned

"Patients will have a difficult time knowing what the results mean"

A photo of a female healthcare worker holding her senior male patient鈥檚 hand.

CMS Announces New Dementia Care Model for Medicare Patients

Aims to provide more coordinated, ongoing care

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Alzheimer's Blood Tests May Improve Primary Care Diagnoses

Without biomarkers, primary care doctors correctly identified Alzheimer's in about 55% of cases

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Study of 1.6 Million Veterans Links Neighborhood and Dementia Risk

Despite equal access to care, health inequalities persisted in disadvantaged areas

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

This Common Device Can Slow Cognitive Decline, Trial Shows

Hearing loss is more than a marker for dementia risk, it appears

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Donanemab Slows Progression in Early Alzheimer's

Safety issues linger, as details of three deaths emerge

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Low Amyloid Burden Bodes Well for Future Dementia Risk

A ray of hope amidst disappointing results from A4 trial

A photo of the vial and packaging of Leqembi.

Registry Enrollment for Alzheimer's Drug Coverage Won't Help Much

A minimalist policy for a minimalist treatment

FDA APPROVED lecanemab (Leqembi) over a computer rendering of amyloid plaque on nerve cells.

Alzheimer's Drug Wins Full FDA Approval

Decision expands lecanemab's Medicare coverage

A photo of a senior man taking a cognitive test.

Without Early Detection, Fighting Dementia Is an Uphill Battle

A brief assessment in primary care can help identify patients most at risk

A photo of the vials and packaging Leqembi for injection.

Our Health Systems Aren't Ready for the Full Approval of Lecanemab

Screening, administration, and eligibility concerns remain

FDA ADCOMM lecanemab over a computer rendering of an antibody bound to an amyloid beta peptide.

Alzheimer's Drug Clears Major Hurdle Toward Full Approval

But risks associated with anti-amyloid agent lecanemab still loom

A photo of a mature man checking his blood sugar levels with a glucose meter.

Study Suggests Increase in Brain Aging in Those With Type 1 Diabetes

But this didn't seem to translate into Alzheimer's disease-related neurodegeneration

An illustration of a physician holding a patient's hand with the text The Doctor's Art - A podcast on Meaning in Medicine

Navigating My Father's Alzheimer's as a Doctor

Sandeep Jauhar, MD, PhD, on his career and wrestling with his father's dementia

A photo composite of a pipette hovering over brain MRI image in the bottom of a well tray.

Alzheimer's Progression Delayed by Rare Genetic Variant

Finding challenges previous assumptions about disease

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