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Cardiac myosin inhibitor linked to improvements in biomarkers in small study

Vast majority of trial participants responded to aficamten

Benefit of the nonsteroidal MRA otherwise consistent across FINEARTS-HF

Splanchnic nerve ablation for volume management passes a feasibility hurdle

Early-phase study analysis suggests potential for remodeling

STRONG-HF analysis details the impact

Autonomic regulation therapy trial showed signal for benefit in terminated pivotal trial

GUIDE-HF trial analysis distinguishes "strata" with different levels of risk

Decision cites insufficient evidence of clinical meaningfulness

STEP-HFpEF trial results come out consistent across ejection fraction

Small randomized trial challenges conventional thinking about sodium

Heart pump placement plus anticoagulation suffice for patients, even those with Afib

Transplant surgeons discuss testing the concept in more humans

Analyses continue to support wider adoption of dapagliflozin, researchers say